Brian Spencer Selected Research

Pathologic Processes

11/2019

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Brian Spencer Research Topics

Disease

37	Parkinson Disease (Parkinson's Disease) 01/2021 - 02/2007
27	Dementia (Dementias) 01/2022 - 06/2008
24	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2007
19	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 02/2007
13	Synucleinopathies 01/2021 - 01/2012
8	Lewy Body Disease (Lewy Body Dementia) 01/2019 - 09/2008
6	Amyloidosis 05/2022 - 08/2008
6	Nervous System Diseases (Neurological Disorders) 01/2021 - 01/2012
6	Neurocognitive Disorders (Clerambault Syndrome) 12/2018 - 02/2013
6	Multiple System Atrophy 01/2017 - 04/2012
5	Neuroinflammatory Diseases 01/2021 - 12/2015
4	Parkinsonian Disorders (Parkinsonism) 03/2016 - 10/2009
3	Immunoglobulin Light-chain Amyloidosis 12/2016 - 11/2007
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2015 - 03/2009
2	Sjogren's Syndrome (Sjogren Syndrome) 05/2022 - 12/2012
2	Tauopathies 01/2021 - 01/2018
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2021 - 03/2014
2	Neoplasms (Cancer) 01/2017 - 12/2015
2	Memory Disorders (Memory Loss) 07/2014 - 01/2011
2	Huntington Disease (Huntington's Disease) 03/2014 - 07/2012
2	Amyloid Plaque 11/2008 - 08/2008
1	Cardiomyopathies (Cardiomyopathy) 05/2022
1	COVID-19 01/2021
1	Pathologic Processes 11/2019
1	Pick Disease of the Brain (Pick's Disease) 01/2018
1	Infections 01/2017
1	Frontotemporal Dementia (Semantic Dementia) 01/2016
1	Gliosis 12/2015
1	Ataxia (Dyssynergia) 09/2015
1	HIV Infections (HIV Infection) 02/2015
1	Hepatomegaly 01/2015
1	Pain (Aches) 01/2015
1	AIDS Dementia Complex 01/2015
1	Corticobasal Degeneration 03/2014
1	Inflammation (Inflammations) 09/2013
1	Rheumatoid Arthritis 05/2013
1	Familial Amyloidosis (Hereditary Amyloidosis) 12/2012
1	Weight Loss (Weight Reduction) 12/2012
1	Diarrhea 12/2012
1	Abdominal Pain (Pain, Abdominal) 12/2012
1	Genomic Instability 09/2012

Drug/Important Bio-Agent (IBA)

29	SynucleinsIBA 01/2021 - 03/2011
21	Proteins (Proteins, Gene)FDA Link 05/2022 - 02/2007
16	alpha-SynucleinIBA 01/2017 - 02/2007
8	Amyloid (Amyloid Fibrils)IBA 01/2019 - 11/2007
6	Amyloid beta-PeptidesIBA 01/2021 - 06/2008
5	Peptides (Polypeptides)IBA 01/2019 - 08/2008
3	Apolipoproteins B (ApoB)IBA 01/2022 - 01/2015
3	EnzymesIBA 01/2021 - 01/2009
3	Toll-Like Receptor 2IBA 01/2021 - 10/2015
3	Pharmaceutical PreparationsIBA 11/2019 - 12/2015
3	AntibodiesIBA 01/2017 - 07/2014
3	Beclin-1IBA 09/2013 - 06/2008
3	Neprilysin (Neutral Endopeptidase)IBA 01/2011 - 11/2008
2	Single-Chain AntibodiesIBA 01/2022 - 01/2018
2	Immunoglobulin FragmentsIBA 01/2022 - 01/2018
2	Protein Isoforms (Isoforms)IBA 01/2021 - 08/2008
2	MicroRNAs (MicroRNA)IBA 01/2017 - 03/2014
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2017 - 01/2016
2	tau Proteins (tau Protein)IBA 01/2017 - 01/2016
2	Immunoglobulins (Immunoglobulin)IBA 12/2016 - 03/2009
2	Neuropeptide YIBA 01/2016 - 01/2009
2	Protein AggregatesIBA 01/2016 - 09/2010
2	Serine Proteases (Serine Protease)IBA 09/2015 - 01/2013
2	EndopeptidasesIBA 06/2014 - 01/2009
2	Amyloidogenic ProteinsIBA 12/2012 - 08/2008
2	ProteomeIBA 09/2012 - 08/2008
2	CalciumIBA 07/2012 - 03/2009
1	Proline (L-Proline)FDA Link 05/2022
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2021
1	Monoclonal AntibodiesIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	DNA Transposable Elements (Element, IS)IBA 01/2021
1	Adenosine Monophosphate (AMP)IBA 01/2021
1	Small Interfering RNA (siRNA)IBA 01/2019
1	OligonucleotidesIBA 01/2019
1	Diflunisal (Dolobid)FDA Link 10/2018
1	Apolipoprotein A-II (Apolipoprotein A2)IBA 11/2017
1	Lenalidomide (CC 5013)FDA Link 01/2017
1	Sunitinib (Sutent)FDA Link 01/2017
1	Endosomal Sorting Complexes Required for TransportIBA 03/2016
1	Retinaldehyde (Retinal)IBA 01/2016
1	PrionsIBA 01/2016
1	Glucosylceramidase (Glucocerebrosidase)IBA 01/2016
1	Nerve Growth Factor (NGF)IBA 01/2016
1	penetratinIBA 01/2016
1	hypoestoxideIBA 12/2015
1	CytokinesIBA 12/2015
1	Dopamine (Intropin)FDA LinkGeneric 09/2015
1	Alkaline PhosphataseIBA 01/2015
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 07/2014
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2013
1	Muramidase (Lysozyme)IBA 12/2012

Therapy/Procedure

9	Therapeutics 01/2021 - 02/2007
8	Immunotherapy 01/2019 - 01/2014
2	Drug Therapy (Chemotherapy) 12/2019 - 01/2015
1	Organ Transplantation 05/2022
1	Injections 01/2019
1	Art Therapy 12/2018
1	Transplantation 04/2014